High prevalence of metallo-beta-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil.
نویسندگان
چکیده
Rates of metallo-beta-lactamase and 16S rRNA methylase production were investigated in 51 imipenem-resistant Pseudomonas aeruginosa clinical isolates collected from hospitals in São Paulo, Brazil. Of them, 57% and 75% produced SPM-1 and RmtD, respectively. Of note, 51% produced both enzymes, suggesting that their coproduction is already common in this geographic area.
منابع مشابه
Detection of a single isolate of CTX-M-1-producing Escherichia coli from healthy pigs in Denmark.
1. Kotra LP, Haddad J, Mobashery S. Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance. Antimicrob Agents Chemother 2000; 44: 3249–56. 2. Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007; 45: 88–94. 3. Wachino J, Shibayama K, Kurokawa H et al. Novel plasmidmediated ...
متن کاملThe Determination of Metallo-Beta-Lactamase Enzymes Prevalence in Pseudomonas Aeruginosa using Etest and their Antibiogram Patterns in Kermanshah, Iran
Background & Aims: One of the main causes of nosocomial infection is pseudomonas aeruginosa and carbapenems is one of the most important classes of antibiotics used in the treatment of infections caused by this bacteria. Metallo-beta-lactamase (MBL) production is one of the most important mechanisms of resistance to carbapenems and their increased prevalence is a serious threat to treatment of ...
متن کاملردیابی ژن متالوبتالاکتاماز blaVIM-1 در ایزوله‌های بالینی سودوموناس آئروجینوزا در مشهد
Introduction: Carbapenems are one of the latest drugs for treatment of threatening infections of Pseudomonas aeruginosa. Resistance to these antibiotics is sometimes caused by carbapnmase class B, such as VIM metallo-beta-lactamase (MBL) that is growing in the communities. The aim of this study was to detect the of metallo-beta-lactamase blaVIM-1 gene among clinical isolates of Pseudomonas aeru...
متن کاملPrevalence of Clinically Isolated Metallo-beta-lactamase-producing Pseudomonas aeruginosa, Coding Genes, and Possible Risk Factors in Iran
Background & Objective: The spread of carbapenem-resistant Pseudomonas aeruginosa is a global concern. Metallo-beta-lactamase (MBL) enzymes cause extensive drug resistance among Gram-negative bacteria. The current study aimed at determining the prevalence of MBL-producing P. aeruginosa in Iran. Methods<...
متن کاملblaVIM and blaIMP Genes Detection in Isolates of Carbapenem Resistant P. aeruginosa of Hospitalized Patients in Two Hospitals in Iran
Background & objective: Beta-lactam antibiotics resistance specifically Imipenem and Meropenem, the last choices of treatment, causes fatal events in patients with P.aeruginosa infection. The aim of this study was to detect the VIM and IMP of metallo-beta-lactamase genes in 103 isolates of P. aeruginosa in two Iranian hospitals. <strong...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 51 9 شماره
صفحات -
تاریخ انتشار 2007